WebAbstract. Cocaine is one of the most commonly used substances of abuse. The use of beta-blockers in cocaine induced acute coronary syndrome has long been a matter of debate. While it is widely believed that beta-blockers are contraindicated in cocaine toxicity, there appears to be some recognizable role for certain beta-blockers in ameliorating ... WebCocaine use is associated with increased cardiovascular mortality and can promote acute coronary syndrome (ACS). Use of beta-blockers is controversial in patients who use cocaine, and the safety and efficacy of these medications in ACS in patients actively using cocaine is unknown. We enrolled 90 pa …
Management of Cocaine-Associated Chest Pain and MI
WebOct 19, 2024 · Cocaine abuse is a major worldwide health problem. Patients with acute cocaine toxicity presenting to the emergency department (ED) may require urgent treatment for tachycardia, dysrhythmia, hypertension, and coronary vasospasm, leading to pathological sequelae such as acute coronary syndrome, stroke, and death. WebPatients with cocaine toxicity present with a clinical picture that is almost identical to that of non-cocaine-related ACS. The "typical" patient who presents with cocaine-induced ACS is a male younger than 50 years of age, is a smoker, has used cocaine within several hours before the onset of symptoms, and has few risk factors for CHD. hipp lietuva
Cocaine-Induced Vasoconstriction in the Human …
WebNov 14, 2024 · Coronary artery vasospasm, or smooth muscle constriction of the coronary artery, is an important cause of chest pain syndromes that can lead to myocardial infarction (MI), ventricular... WebObjective: To critically evaluate the 30 year debate of beta-blocker use in cocaine-induced acute coronary syndrome (CIACS). Data sources: An Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, and Ovid MEDLINE (1966-August 21, 2007) search of the medical literature was conducted using the key terms cocaine, … WebApr 1, 2013 · Cocaine toxicity can lead to a mismatch in myocardial oxygen supply and demand through various mechanisms, including vigorous central sympathomimetic stimulation, coronary artery vasoconstriction, platelet … hipp latte 2 minsan