Tanshinone vi
WebMay 8, 2024 · Rationale:Tanshinone, a type of diterpenes derived from salvia miltiorrhiza, is a particularly promising herbal medicine compound for the treatment of cancers including acute myeloid leukemia (AML). Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from Salvia miltiorrhiza. Dihydrotanshinone I has been reported to have cytotoxicity to a variety of tumor cells.
Tanshinone vi
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WebJan 14, 2024 · Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen). Tan IIA is currently used in China and other neighboring countries to treat patients with cardiovascular system, diabetes, apoplexy, arthritis, sepsis, and other … WebFeb 12, 2008 · Effects of tanshinone VI, a diterpene from Tan-Shen, on humoral factor-induced phosphorylation of ERK and Akt during hypertrophy of cardiomyocytes and fibrosis of cardiac fibroblasts isolated from neonatal rats were examined. Treatment of cultured cardiomyocytes with 10 nM insulin-like growth factor-1 (IGF-1) or 10 nM endothelin-1 …
WebExtract of Tan-Shen (Salvia miltiorrhiza, Labiatae), a Chinese traditional crude drug, was reported to show beneficial activity for heart disease. Chemical examination on the extract was performed on the basis of screening for protective action on the ischemic myocardium. Web121064-74-2 Tanshinone VI C18H16O4 TRC Custom Quotation Product Detail All Products are stable to be shipped at room temperature, unless otherwise specified. …
WebNov 1, 2024 · The ROS content in the hippocampal tissue of rats in the 6-OHDA group demonstrated a significant augmentation relative to the control-saline group, so that the highest ROS content was observed in PD rats (Fig. 4 a).The treatments of tanshinone IIA reduced ROS in the hippocampus of rats and the ROS content in the PD group receiving … WebThe tanshinone VI derivatives improved post-hypoxic contractile recovery, which was associated with restoration of tissue ionic concentrations, and diminishment of the release of creatine kinase and ATP metabolites from the hypoxic/reoxygenated hearts. The efficacy of these compounds was similar to that of tanshinone VI.
WebOct 1, 2013 · This study investigated the possible antitumor mechanisms of action of Tanshinone VI, one of the components of Salvia miltiorrhiza Bunge, which is used in …
WebTanshinone. Tanshinones are a class of chemical compounds. Examples include dihydrotanshinone, tanshinone I, or tanshinone IIA. These compounds are all naturally occurring and can all be isolated from Salvia miltiorrhiza. [1] [2] Dihydrotanshinone I has been reported to have cytotoxicity to a variety of tumor cells. goldman sachs headquarters zip codeWebApr 30, 2024 · Role of miR-145 in the effect of Tanshinone II A on HeLa cells (A) qPCR analyses of the relative mRNA levels of miR-145 on HeLa cells at different concentrations (0, 2, 4, 8 μm). Gene expression was normalized to U6 mRNA level. ... Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis … goldman sachs hex codeWebCatalogue Number: T700360: Chemical Name: Tanshinone VI: CAS Number: 121064-74-2: Molecular Formula: C18H16O4: Molecular Weight: 296.32: Category: Standards; Natural ... goldman sachs helocWebThe possible effects of tanshinone VI (tsh), a diterpene from the root of Tan-Shen (Salvia miltiorrhiza, Bunge (Labiatae)) on hypertrophy and fibrosis in cultured neonatal rat cardiac … goldman sachs helios business park bangaloreWebTanshinone IIA is the main effective component of Salvia miltiorrhiza known as 'Danshen' in traditional Chinese medicine for treating cardiovascular disorders. The objective of this … goldman sachs hewitt loginWebTanshinone VI Molecular Formula CHO Average mass 296.317 Da Monoisotopic mass 296.104858 Da ChemSpider ID 131447 More details: Names Properties Searches Spectra … goldman sachs henry paulsonWebAug 1, 2003 · When tanshinone VI was added to cardiac fibroblast-conditioned medium, the medium-mediated hypertrophy of cardiomyocytes was also attenuated. These results show that tanshinone VI may attenuate in ... goldman sachs high interest savings